Asymmetric Dehydrative Allylation Using Soft Ruthenium and Hard Brønsted Acid Combined Catalyst
نویسندگان
چکیده
Abstract Asymmetric Pd‐catalyzed Tsuji‐Trost‐type allylation is an important catalytic reaction toward chiral natural and unnatural product syntheses. We successfully modified a desalt‐type using allyl ester or halide to dehydrative one allylic alcohol via the establishment of two redox‐mediated donor acceptor bifunctional catalyst systems. These systems were cationic CpRu‐Cl‐Napy‐PyCOOH CpRu‐Naph‐diPIM‐dioxo‐ i Pr/ p ‐TsOH designed on basis soft ruthenium hard Brønsted acid combined concept. The complementary use catalysts for asymmetric expands application scope facilitating utilization both aliphatic aromatic alcohols with various nucleophiles in substrate. In this account, design, synthesis, these reported.
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ژورنال
عنوان ژورنال: Chemical Record
سال: 2021
ISSN: ['1527-8999', '1528-0691']
DOI: https://doi.org/10.1002/tcr.202000157